Activity of Cathepsin B and Proteome in the Serum and Brain of Rats with Different Behavioral Activity under Conditions of Metabolic Stress
| Autor: | N. V. Kirbaeva, A. V. Vasil’ev, A.D. Malinkin, N. E. Sharanova |
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| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Male Proteomics medicine.medical_specialty Proteome Ubiquinone Biology General Biochemistry Genetics and Molecular Biology Cathepsin B 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Stress Physiological Internal medicine medicine Animals Metabolic Stress Rats Wistar Coenzyme Q10 Behavior Animal Brain General Medicine Rats 030104 developmental biology Endocrinology chemistry Cathepsin B activity Proteolysis Adaptation Lysosomes 030217 neurology & neurosurgery |
| Zdroj: | Bulletin of experimental biology and medicine. 165(6) |
| ISSN: | 1573-8221 |
| Popis: | Study of the brain and serum of male Wistar rats with the metabolic stress model detected changed proteomic profiles of emotiogenic structures and an increase of cathepsin B activity. Antiapoptotic effect of coenzyme Q10, added to the ration, was detected. Differences in the adaptation response of animals with passive and active behavior under conditions of metabolic stress were detected. |
| Databáze: | OpenAIRE |
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