The rs13075270 and rs13092160 polymorphisms of CCR1 and CCR3 genes on oral aphthous-like lesions in PFAPA syndrome

Autor:	Weiwei, Li, Na, Li, Guohai, Yang, Yanhua, Li
Rok vydání:	2022
Předmět:	Fever Lymphadenitis Receptors CCR3 Receptors CCR1 Humans Pharyngitis Stomatitis Aphthous Syndrome General Medicine Child Familial Mediterranean Fever
Zdroj:	Cellular and Molecular Biology. 67:328-333
ISSN:	1165-158X 0145-5680
DOI:	10.14715/cmb/2021.67.4.37
Popis:	Fever is a common symptom of infection in children. Periodic fever syndromes are less common but more complex. One of these Periodic fever syndromes is PFAPA (periodic fever, aphthous stomatitis, pharyngitis, cervical adenitis) syndrome which is known as the most benign syndromes. The cause of this disease is unknown. Various factors, including environmental and genetic factors, are involved in the development of this disease. In this study, the association of rs13075270 and rs13092160 polymorphisms were investigated in CCR1 and CCR3 genes with susceptibility to this syndrome in the Chinese population. In this regard, 38 patients with PFAPA syndrome and 100 healthy individuals were selected. After DNA sampling and extraction, polymorphisms of CCR1 and CCR3 receptor genes were examined by the PCR-RFLP method. Findings were analyzed using SPSS software version 22 with a significant level of P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35f47bfbb92ee7df015c491f0e303cbe https://doi.org/10.14715/cmb/2021.67.4.37 Zobrazit plný text záznamu