Phi 6 bacteriophage inactivation by metal salts, metal powders, and metal surfaces
| Autor: | Katja Molan, Ramin Rahmani, Daniel Krklec, Miha Brojan, David Stopar |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
Ceramics
Silver kovinski ioni Surface Properties soli composite materials Temperature technology industry and agriculture bakteriofagi metals kompoziti ceramic–metal powders Hydrogen-Ion Concentration udc:578.347:615.281.8:546.3 bacteriophage (phage) Phi6 metal salts Bacteriophage phi 6 Infectious Diseases prah Virology Phi 6 Powders Copper |
| Zdroj: | Viruses, vol. 14, no. 2, 204, 2022. Viruses; Volume 14; Issue 2; Pages: 204 |
| ISSN: | 1999-4915 |
| Popis: | The interaction of phages with abiotic environmental surfaces is usually an understudied field of phage ecology. In this study, we investigated the virucidal potential of different metal salts, metal and ceramic powders doped with Ag and Cu ions, and newly fabricated ceramic and metal surfaces against Phi6 bacteriophage. The new materials were fabricated by spark plasma sintering (SPS) and/or selective laser melting (SLM) techniques and had different surface free energies and infiltration features. We show that inactivation of Phi6 in solutions with Ag and Cu ions can be as effective as inactivation by pH, temperature, or UV. Adding powder to Ag and Cu ion solutions decreased their virucidal effect. The newly fabricated ceramic and metal surfaces showed very good virucidal activity. In particular, 45%TiO2 + 5%Ag + 45%ZrO2 + 5%Cu, in addition to virus adhesion, showed virucidal and infiltration properties. The results indicate that more than 99.99% of viruses deposited on the new ceramic surface were inactivated or irreversibly attached to it. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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