National Surveillance of Spotted Fever Group Rickettsioses in the United States, 2008-2012
| Autor: | Christopher D. Paddock, Casey Barton Behravesh, Kristen Nichols Heitman, Naomi A. Drexler, F. Scott Dahlgren, Robert F. Massung |
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| Rok vydání: | 2015 |
| Předmět: |
0301 basic medicine
Adult Male medicine.medical_specialty Time Factors 030231 tropical medicine 030106 microbiology Rickettsiaceae Infections 03 medical and health sciences 0302 clinical medicine Species Specificity Risk Factors Virology Internal medicine Epidemiology Case fatality rate medicine Humans Rickettsia Child Disease Notification biology Incidence (epidemiology) Incidence Racial Groups Articles Rickettsia rickettsii biology.organism_classification medicine.disease United States Spotted fever Infectious Diseases Rickettsiosis Population Surveillance Pacific islanders Parasitology Female |
| Zdroj: | The American journal of tropical medicine and hygiene. 94(1) |
| ISSN: | 1476-1645 |
| Popis: | Spotted fever group (SFG) rickettsioses are notifiable conditions in the United States caused by the highly pathogenic Rickettsia rickettsii and less pathogenic rickettsial species such as Rickettsia parkeri and Rickettsia sp. 364D. Surveillance data from 2008 to 2012 for SFG rickettsioses are summarized. Incidence increased from 1.7 cases per million person-years (PY) in 2000 to 14.3 cases per million PY in 2012. During 2008-2012, cases of SFG rickettsiosis were more frequently reported among males, persons of white race, and non-Hispanic ethnicity. Overall, case fatality rate (CFR) was low (0.4%), however, risk of death was significantly higher for American Indian/Alaska Natives (relative risk [RR] = 5.4) and Asian/Pacific Islanders (RR = 5.7) compared with persons of white race. Children aged < 10 years continue to experience the highest CFR (1.6%). Higher incidence of SFG rickettsioses and decreased CFR likely result from increased reporting of tick-borne disease including those caused by less pathogenic species. Recently, fewer cases have been confirmed using species-specific laboratory methods (such as cell culture and DNA detection using polymerase chain reaction [PCR] assays), causing a clouded epidemiological picture. Use of PCR and improved documentation of clinical signs, such as eschars, will better differentiate risk factors, incidence, and clinical outcomes of specific rickettsioses in the future. |
| Databáze: | OpenAIRE |
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