Fluorescent Probes for Sugar Detection
| Autor: | Colm Delaney, Danielle Bruen, Larisa Florea, Dermot Diamond |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Anions
Fluorophore Materials science Polymers 02 engineering and technology 010402 general chemistry Photochemistry 01 natural sciences Viologens Pyranine chemistry.chemical_compound Monosaccharide General Materials Science Arylsulfonates Fluorescent Dyes chemistry.chemical_classification Monosaccharides Cationic polymerization Esters Hydrogels 021001 nanoscience & nanotechnology Fluorescence 0104 chemical sciences Solutions Glucose Spectrometry Fluorescence Monomer chemistry Self-healing hydrogels Sugars 0210 nano-technology Boronic acid |
| Zdroj: | ACS Applied Materials & Interfaces. 10:38431-38437 |
| ISSN: | 1944-8252 1944-8244 |
| Popis: | Herein, a new class of polymerizable boronic acid (BA) monomers are presented, which are used to generate soft hydrogels capable of accurate determination of saccharide concentration. By exploiting the interaction of these cationic BAs with an anionic fluorophore, 8-hydroxypyrene-1,3,6-trisulfonic acid trisodium salt (pyranine), a two-component sugar-sensing system was realized. In the presence of such cationic BAs ( o-BA, m-BA, and p-BA), the fluorescence of pyranine becomes quenched because of the formation of a nonfluorescent BA-fluorophore complex. Upon addition of saccharides, formation of a cyclic boronate ester results in dissociation of the nonfluorescent complex and recovery of the pyranine fluorescence. The response of this system was examined in solution with common monosaccharides, such as glucose, fructose, and galactose. Subsequent polymerization of the BA monomers yielded cross-linked hydrogels which showed similar reversible recovery of fluorescence in the presence of glucose. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|