Papillary thyroid carcinoma in three siblings with familial adenomatous polyposis
| Autor: | B. Civitelli, G. Tanzini, Francesco Cetta, M. C. Pacchiarotti, M. Petracci, Serenella Civitelli |
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| Rok vydání: | 1996 |
| Předmět: |
Adult
medicine.medical_specialty Pathology Familial adenomatous polyposis Neoplasms Multiple Primary Thyroid carcinoma Gardner Syndrome Internal medicine Biopsy medicine Humans Thyroid Neoplasms Family Health medicine.diagnostic_test business.industry Biopsy Needle Thyroid Gastroenterology Nodule (medicine) Hepatology medicine.disease Carcinoma Papillary Pedigree medicine.anatomical_structure Adenomatous Polyposis Coli Female medicine.symptom business Aunt |
| Zdroj: | International Journal of Colorectal Disease. 11:34-37 |
| ISSN: | 1432-1262 0179-1958 |
| DOI: | 10.1007/bf00418853 |
| Popis: | The authors report three siblings (two sisters and their aunt, aged 20, 22 and 36, respectively) with familial adenomatous polyposis (FAP) and papillary thyroid carcinoma. After diagnosis of FAP, a single, non palpable nodule was revealed in each patient by routine screening ultrasonography of the gland. The diagnosis of papillary carcinoma was made by fine-needle-aspiration biopsy of the nodules and confirmed by histologic examination of surgical specimens. A review of the literature reveals about 40 reports of such an association, that is considered not fortuitous. Nevertheless, in this family the association seems to be a distinctive, clinical feature of the syndrome, affecting three out of five members intensively screened for extracolonic lesions. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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