Gender differences in predictors of intensive care units admission among COVID-19 patients: The results of the SARS-RAS study of the Italian Society of Hypertension

Autor: Iaccarino G, Grassi G, Borghi C, Carugo S, Fallo F, Ferri C, Giannattasio C, Grassi D, Letizia C, Mancusi C, Minuz P, Perlini S, Pucci G, Rizzoni D, Salvetti M, Sarzani R, Sechi L, Veglio F, Volpe M, Muiesan ML, SARS-RAS Investigators
Přispěvatelé: Iaccarino G, Grassi G, Borghi C, Carugo S, Fallo F, Ferri C, Giannattasio C, Grassi D, Letizia C, Mancusi C, Minuz P, Perlini S, Pucci G, Rizzoni D, Salvetti M, Sarzani R, Sechi L, Veglio F, Volpe M, Muiesan ML, SARS-RAS Investigators, Iaccarino, G, Grassi, G, Borghi, C, Carugo, S, Fallo, F, Ferri, C, Giannattasio, C, Grassi, D, Letizia, C, Mancusi, C, Minuz, P, Perlini, S, Pucci, G, Rizzoni, D, Salvetti, M, Sarzani, R, Sechi, L, Veglio, F, Volpe, M, Muiesan, M, Iaccarino, G., Borghi, C., Carugo, S., Fallo, F., Ferri, C., Giannattasio, C., Grassi, D., Letizia, C., Mancusi, C., Minuz, P., Perlini, S., Pucci, G., Rizzoni, D., Salvetti, M., Sarzani, R., Sechi, L., Veglio, F., Volpe, M., Muiesan, M. L., SARS-RAS Investigator
Rok vydání: 2020
Předmět:
COVID-19
gender
obesity
Male
Pulmonology
Cross-sectional study
Disease
Cardiovascular Medicine
covid
gender
Vascular Medicine
Severity of Illness Index
Covid
law.invention
Adolescent
Adult
Aged
Aged
80 and over
Betacoronavirus
Coronavirus Infections
Cross-Sectional Studies
Female
Heart Failure
Humans
Hypertension
Italy
Middle Aged
Obesity
Pandemics
Pneumonia
Viral
Renal Insufficiency
Chronic
Risk Factors
Sex Factors
Young Adult
Intensive Care Units
Patient Admission
0302 clinical medicine
Medical Conditions
Endocrinology
Health care
80 and over
Medicine
Chronic
Nephrology
Cardiovascular Diseases
Human
medicine.medical_specialty
Endocrine Disorders
Science
Intensive Care Unit
COVID-19
SARS-CoV-2
03 medical and health sciences
Intensive care
Severity of illness
Renal Diseases
Diabetes Mellitus
Cross-Sectional Studie
Betacoronaviru
Biology and Life Sciences
Correction
Covid 19
Pneumonia
Clinical trial
Health Care
Health Care Facilities
Observational study
SARS_CoV-2
Viral Diseases
Physiology
Sex Factor
030204 cardiovascular system & hematology
law
Chronic Kidney Disease
Medicine and Health Sciences
Coronary Heart Disease
030212 general & internal medicine
Viral
Renal Insufficiency
intensive care
Multidisciplinary
SARS_CoV-2
Gender
intensive care
prediction
Intensive care unit
Hospitals
Infectious Diseases
Physiological Parameters
Research Article
Chronic Obstructive Pulmonary Disease
Cardiology
Pandemic
business.industry
Coronavirus Infection
Risk Factor
Body Weight
Gender
prediction
Hyperyension
Metabolic Disorders
Emergency medicine
business
Zdroj: PLoS ONE, Vol 15, Iss 10, p e0237297 (2020)
PLoS ONE
PLoS ONE, Vol 16, Iss 9, p e0257181 (2021)
ISSN: 1932-6203
Popis: BackgroundThe global rate of intensive care unit (ICU) admission during the COVID-19 pandemic varies within countries and is among the main challenges for health care systems worldwide. Conflicting results have been reported about the response to coronavirus infection and COVID-19 outcomes in men and women. Understanding predictors of intensive care unit admission might be of help for future planning and management of the disease.Methods and findingsWe designed a cross-sectional observational multicenter nationwide survey in Italy to understand gender-related clinical predictors of ICU admission in patients with COVID-19. We analyzed information from 2378 charts of Italian patients certified for COVID-19 admitted in 26 hospitals. Three hundred ninety-five patients (16.6%) required ICU admission due to COVID19 infection, more frequently men (74%), with a higher prevalence of comorbidities (1,78±0,06 vs 1,54±0,03 pConclusionsOur study demonstrates that gender is the primary determinant of the disease's severity among COVID-19. Obesity is the condition more often observed among those admitted to ICU within both genders.Trial registrationClinicaltrials.gov: NCT04331574.
Databáze: OpenAIRE
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