Assessment in rats of a new bioerodible bone-wax-like polymer
| Autor: | Einar Sudmann, Gisle Bang, Hanna Strømme Koppang, Ole-Gunnar Anfinsen, Rolf Koppang, Steinar Ørbeck Stølen, Bjørn Sudmann |
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| Rok vydání: | 1993 |
| Předmět: |
Male
musculoskeletal diseases Polyesters Bone wax Palmitates Dentistry Biocompatible Materials Bone healing Iliac crest Hemostatics Beeswax Ilium Abdominal muscles Materials Testing medicine Animals Orthopedics and Sports Medicine Tibia Rats Wistar Abdominal Muscles Inflammation Wound Healing business.industry Foreign-Body Reaction Skull Prostheses and Implants Anatomy musculoskeletal system Rats Drug Combinations Biodegradation Environmental medicine.anatomical_structure Waxes visual_art visual_art.visual_art_medium Surgery Implant business |
| Zdroj: | Acta Orthopaedica Scandinavica. 64:336-339 |
| ISSN: | 0001-6470 |
| DOI: | 10.3109/17453679308993639 |
| Popis: | Holes drilled in rats' skull, iliac crest, and tibia were filled with beeswax or with a new, wax-like, bioerodible polyorthoester (Alzamer®). Empty drill-holes served as controls. In addition, beeswax and polyorthoester were deposited between the left and the right oblique abdominal muscles, respectively. In muscle, both the beeswax and polyorthoester elicited a transient foreign body reaction. The beeswax was not resorbed in bone or muscle, whereas the polyorthoester was. Bone healing was inhibited in the iliac crest and the tibiae filled with beeswax, whereas holes filled with polyorthoester healed readily. |
| Databáze: | OpenAIRE |
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