Uptake of Main Fractions of Labelled Bleomycin by Solid Ehrlich Ascites Tumours in Mice
| Autor: | Krawczyk Z, Rembelska M, Koniarek B, Liniecki J |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
medicine.diagnostic_test
business.industry Muscles Bleomycinic acid General Medicine Pharmacology Ehrlich ascites Bleomycin Scintigraphy Bone and Bones Mice chemistry.chemical_compound chemistry Immunology Animals Medicine Radiology Nuclear Medicine and imaging Cobalt Radioisotopes Carcinoma Ehrlich Tumor business Neoplasm Transplantation |
| Zdroj: | Nuklearmedizin. 23:127-129 |
| ISSN: | 2567-6407 0029-5566 |
| DOI: | 10.1055/s-0038-1624206 |
| Popis: | SummaryConcentrations were studied of 58Co in the solid Ehrlich ascites tumour, blood, muscle and bone of male Swiss mice administered as complexed with total bleomycin commercially available and its isolated fractions A2, B2, demethyl A2, A1, A5, B4 and bleomycinic acid. The tumour/ non-tumour ratios were determined 24 hrs after injection of the complexes. The ratios for fraction A2, B2 and total bleomycin were very close to each other. The remaining fractions showed lower values of the ratios. These results suggest that it is unlikely that any of the fractions studied are superior to total labelled bleomycin with respect to tumour scintigraphy. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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