Electrochemiluminescence Imaging for Bioanalysis
Autor: | Dechen Jiang, Neso Sojic, Stéphane Arbault, Jingjing Zhang |
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Přispěvatelé: | China Agricultural University (CAU), Institut des Sciences Moléculaires (ISM), Université Montesquieu - Bordeaux 4-Université Sciences et Technologies - Bordeaux 1-École Nationale Supérieure de Chimie et de Physique de Bordeaux (ENSCPB)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS) |
Jazyk: | angličtina |
Rok vydání: | 2019 |
Předmět: |
Bioanalysis
endocrine system Materials science Luminescence spatial/temporal resolutions bipolar electrochemistry multiplex bioassay Biosensing Techniques 010402 general chemistry 01 natural sciences Signal Analytical Chemistry [CHIM.ANAL]Chemical Sciences/Analytical chemistry Bipolar electrochemistry Electrochemiluminescence Humans 010405 organic chemistry business.industry single cells/particles Analytical technique co-reactant pathway Electrochemical Techniques 0104 chemical sciences Electrochemiluminescence imaging [CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistry Electrode Luminescent Measurements Optoelectronics Single-Cell Analysis business |
Zdroj: | Annual Review of Analytical Chemistry Annual Review of Analytical Chemistry, Annual Reviews, 2019, 12 (1), pp.275-295. ⟨10.1146/annurev-anchem-061318-115226⟩ |
ISSN: | 1936-1327 1936-1335 |
Popis: | International audience; Electrochemiluminescence (ECL) is a widely used analytical technique with the advantages of high sensitivity and low background signal. The recently fast development of electrochemical materials, luminophores and optical elements significantly increase the ECL signals, and thus, the ECL imaging with enhanced spatial and temporal resolutions is realized. Currently, ECL imaging has been successfully applied in high throughput bioanalysis and to visualize the distribution of molecules at single cells. Compared with other optical bioassays, no optical excitation is involved in imaging approach so that it avoids background signal from the illumination and increases the detection sensitivity. This review highlights some of the most exciting developments in this field, including the mechanisms, the electrode designs and the applications of ECL imaging in bioanalysis and at single cells and particles. |
Databáze: | OpenAIRE |
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