Targeted alterations in iron homeostasis underlie plant defense responses
| Autor: | Yangdou Wei, Guosheng Liu, Ramaswami Sammynaiken, Gopalan Selvaraj, David L. Greenshields, Rozina Hirji |
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| Rok vydání: | 2007 |
| Předmět: |
inorganic chemicals
Iron Overload Iron Molecular Sequence Data Gene Expression Hydrogen Peroxide Cell Biology Biology Models Biological Respiratory burst Cell biology Plant Leaves Cell wall Mediator Ascomycota Transcription (biology) Botany Plant defense against herbivory Homeostasis Secretion Efflux Reactive Oxygen Species Plant Physiological Phenomena Triticum Intracellular |
| Zdroj: | Journal of Cell Science. 120:596-605 |
| ISSN: | 1477-9137 0021-9533 |
| DOI: | 10.1242/jcs.001362 |
| Popis: | Iron (Fe) is a ubiquitous redox-active element essential for most life. The formation of localized cell wall appositions, the oxidative burst and the production of pathogenesis-related proteins are hallmarks of plant defense responses. Here, we report that iron is a central mediator linking these three phenomena. We show that in response to pathogen attack, reactive Fe3+, but not Fe2+, is deposited at cell wall appositions where it accumulates and mediates the oxidative burst. We provide evidence that the bulk secretion of Fe3+ provoked by pathogen attack leads to intracellular iron depletion, and that H2O2 itself induces ATP-dependent intracellular iron efflux. Finally, we demonstrate that this intracellular iron depletion promotes the transcription of pathogenesis-related genes in concert with H2O2. This work identifies iron as an underlying factor associated with the oxidative burst and regulating cereal defenses, and establishes links between disease-related iron homeostasis in plants and animals. |
| Databáze: | OpenAIRE |
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