Evaluation of genotoxicity and cytotoxicity of inhabitants of Vila Rural Água Viva, Brazil, exposed to agrochemicals using the micronucleus buccal cytome assay

Autor: Patricia Aline, Bressiani, Geiciane Locatelli, Alves, Inara Giacobbo, de Marco, Mariana Tonello, Biffi, Sabrina, Ishikawa, Fernando César, Manosso, Eduardo Michel Vieira, Gomes, Ticiane Sauer, Pokrywiecki, Ana Paula de Oliveira, Schmitz, Elisângela, Düsman
Rok vydání: 2022
Předmět:
Zdroj: Environmental Toxicology and Pharmacology. 96:104002
ISSN: 1382-6689
DOI: 10.1016/j.etap.2022.104002
Popis: The aim of this study was to carry out a pilot investigation, using a buccal micronucleus cytome assay, with the population of Vila Rural Água Viva (Francisco Beltrão, Paraná, Brazil), environmentally exposed to agrochemicals. The data shows statistically differences between the control group (not exposed) and the population of Vila Rural regarding the cytotoxicity and mutagenicity. There was no significant change between the average relative frequencies of these data whether divided between smokers and non-smokers, or practitioners of physical activities or not. It was also observed that age or time of exposure to agrochemicals did not show a linear relationship with the average relative frequencies of cytotoxicity and mutagenicity data. The work shows the presence of 2,4-D herbicide in water sample of community, then it is hoped that the results will assist in guiding the dangers to health and the environment from exposure to agrochemicals.
Databáze: OpenAIRE