The relationship between smell identification and neuropsychological domains: Results from a sample of community-dwelling adults suspected of dementia
| Autor: | A Schmitt, Amy E. Werry, W Goette |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Male
050103 clinical psychology Repeatable Battery for the Assessment of Neuropsychological Status Elementary cognitive task Mediation (statistics) Olfaction Neuropsychological Tests 03 medical and health sciences Olfaction Disorders 0302 clinical medicine Neuroimaging Memory medicine Dementia Humans Learning 0501 psychology and cognitive sciences Aged Aged 80 and over 05 social sciences Neuropsychology Wechsler Scales Middle Aged medicine.disease Test (assessment) Smell Clinical Psychology Neurology Reading Mental Recall Female Neurology (clinical) Independent Living Psychology 030217 neurology & neurosurgery Psychomotor Performance Clinical psychology |
| Zdroj: | Journal of clinical and experimental neuropsychology. 40(6) |
| ISSN: | 1744-411X |
| Popis: | This study aimed to test the theoretical relationships between smell identification and cognitive tasks based on existing neuroimaging and anatomical findings.Utilizing data collected from a memory assessment clinic, theory-derived mediation and moderation models were tested. The sample used in this study consisted of 103 (39 male, 64 female) individuals referred for memory assessments. The sample's mean education was 12.4 years (SD = 3.2), and the mean age of the sample was 77.2 years (SD = 6.3).The University of Pennsylvania Smell Identification Test (UPSIT) was a significant, partial mediator of the relationship between the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) Immediate and Delayed Memory indexes. Olfactory identification did not mediate list learning and retrieval; however, olfactory identification was a significant partial mediator of the relationship between story encoding and later memory retrieval of the story. Olfactory identification also fully mediated the relationship between a visuospatial construction task and its reconstruction from memory after a short delay. The relationship between processing speed and the olfactory identification was significantly mediated by semantic memory. Finally, the UPSIT moderated the relationship between a measure of premorbid ability, the Wechsler Test of Adult Reading, and current global cognitive functioning.Our results support theoretical relationships between olfaction and neuropsychological domains. Additionally, our results suggest that the UPSIT may serve as a proxy for cerebral integrity and is likely related to the duration of neurodegeneration. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|