Population Based Analysis Ependymoma Patients in Alberta from 1975 to 2007
| Autor: | Robert Nordal, Yves Starreveld, Jacob C. Easaw, Bradly J. Biagioni, Mark G. Hamilton, Amitabh D Singh, Jennifer A. Chan, Paula de Robles, Roger Y. Tsang, Gerald Lim, Gloria B. Roldán Urgoiti |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Adult
Male Ependymoma medicine.medical_specialty Adolescent Population Postoperative radiotherapy Population based Alberta Young Adult Internal medicine Humans Medicine Spinal Cord Neoplasms Progression-free survival Young adult Child education Retrospective Studies education.field_of_study Brain Neoplasms business.industry Infant Newborn Infant Retrospective cohort study Subtotal Resection General Medicine Middle Aged medicine.disease Survival Rate Neurology Child Preschool Population Surveillance Female Neurology (clinical) business Follow-Up Studies |
| Zdroj: | Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques. 41:742-747 |
| ISSN: | 2057-0155 0317-1671 |
| DOI: | 10.1017/cjn.2014.107 |
| Popis: | Background: Ependymomas are rare tumors of the central nervous system whose management is controversial. This population-based study of adults and children with ependymoma aims to (1) identify clinical and treatment-related factors that impact survival and (2) determine if postoperative radiotherapy (RT) can improve survival of patients with subtotal resection (STR) to levels similar to patients who had gross total resection (GTR). Methods: This retrospective population-based study evaluated 158 patients with ependymoma diagnosed between 1975-2007 in Alberta, Canada. Results: Younger patients (Conclusions: This is the first Canadian population-based analysis of patients with ependymoma including adults and children. Extent of resection appears to be the most important factor determining overall survival. Importantly, the addition of RT to patients initially treated with STR does not improve survival to levels similar to patients receiving GTR. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|