Impact of SARS-CoV-2 on the clinical outcomes and placental pathology of pregnant women and their infants: A systematic review
| Autor: | Cameron Bardwell, Na Zeng, Brittany Ruschkowski, Jason Tran, Youssef Nasr, Irina Oltean, Joseph de Nanassy, Sarah Lawrence, Dina El Demellawy |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Coronavirus disease 2019 (COVID-19) Placenta diseases Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Review Article Disease Preeclampsia law.invention 03 medical and health sciences 0302 clinical medicine law medicine Placental pathology lcsh:Social sciences (General) lcsh:Science (General) Pregnancy Multidisciplinary Obstetrics business.industry SARS-CoV-2 Pregnant women COVID-19 Neonates medicine.disease Intensive care unit Gestational diabetes 030104 developmental biology lcsh:H1-99 business 030217 neurology & neurosurgery lcsh:Q1-390 |
| Zdroj: | Heliyon, Vol 7, Iss 3, Pp e06393-(2021) Heliyon |
| ISSN: | 2405-8440 |
| Popis: | Pregnant women are susceptible to viral infections due to physiological changes such as cell-mediated immunity. No severe adverse pregnancy or neonatal outcomes have been consistently reported in 2019 novel coronavirus disease (COVID-19) positive pregnancy cases. There are controversies around the role of COVID-19 in pregnancy. A systematic review was conducted to examine clinical maternal and neonatal clinical outcomes. Studies were included if they reported SARS-CoV-2 infection among pregnant women and/or COVID-19 positive neonates as validated by positive antibody testing or viral testing using polymerase chain reaction. Case series, case reports, case-control studies, and comparative studies were included. Eight hundred and thirty-seven records were identified, resulting in 525 records for level I screening. Forty-one were included after full-text review. Results suggest elevated rates of intensive care unit (ICU) admission, gestational diabetes, preeclampsia, C-sections, pre-term birth, and C-reactive protein (CRP) in comparison to pregnant women without SARS-CoV-2. Careful monitoring of pregnancies with SARS-CoV-2 to minimize adverse clinical outcomes is recommended. |
| Databáze: | OpenAIRE |
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