Additional file 1 of Shank2 identifies a subset of glycinergic neurons involved in altered nociception in an autism model

Autor: Olde Heuvel, Florian, Ouali Alami, Najwa, Aousji, Oumayma, Pogatzki-Zahn, Esther, Zahn, Peter K., Wilhelm, Hanna, Deshpande, Dhruva, Khatamsaz, Elmira, Catanese, Alberto, Woelfle, Sarah, Schön, Michael, Jain, Sanjay, Grabrucker, Stefanie, Ludolph, Albert C., Verpelli, Chiara, Michaelis, Jens, Boeckers, Tobias M., Roselli, Francesco
Rok vydání: 2023
DOI: 10.6084/m9.figshare.23519976.v1
Popis: Additional file 1: Figure S1: Shank2 spinal cord localisation. Figure S2 Shank2 architecture and localisation. Figure S3 Loss of Shank2 immunoreactivity in cerebral cortex from Shank2−/− mice. Figure S4 CTB-488 injections reveal cutaneous afferents on Shank2high expressing neurons. Figure S5 No difference in neuronal architecture in the spinal cord of Shank2−/− mice. Figure S6 No difference in inhibitory synapses in the spinal cord of Shank2−/− mice. Figure S7 Increased number of cFos mRNA + interneurons in Laminae I upon Formalin injection. Table S1 Primary and secondary antibodies used for immunostainingFluorescent in Situ Hybridisationor for western blot. Table S2 Full details regarding human samples. Source data file 1 uncropped Western Blot of Shank2 in mouse tissue.
Databáze: OpenAIRE