Visual function assessment in simulated real-life situations in patients with age-related macular degeneration compared to normal subjects
| Autor: | William R. Freeman, Gutstein W, Stanley P. Azen, Giulio Barteselli, Dirk-Uwe Bartsch, Jay Chhablani, Maria Laura Gomez, Aubrey L. Doede, Laurie Dustin |
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| Rok vydání: | 2014 |
| Předmět: |
Male
Aging Visual acuity Light genetic structures Mesopic vision Mesopic Vision Visual Acuity Glaucoma Neurodegenerative Eye Ophthalmology & Optometry Glare Neuro-ophthalmology Macular Degeneration 80 and over Contrast (vision) Prospective Studies media_common Aged 80 and over Vision Tests Middle Aged Healthy Volunteers Female medicine.symptom Adult medicine.medical_specialty media_common.quotation_subject Clinical Sciences Immunology Vision Disorders Ophthalmic pathology Contrast Sensitivity Young Adult Clinical Research Opthalmology and Optometry Geographic Atrophy Ophthalmology medicine Humans Vision test Eye Disease and Disorders of Vision Aged business.industry Reproducibility of Results Macular degeneration medicine.disease eye diseases Clinical Study Wet Macular Degeneration Optometry sense organs business |
| Zdroj: | Eye (London, England), vol 28, iss 10 |
| ISSN: | 1476-5454 0950-222X |
| DOI: | 10.1038/eye.2014.189 |
| Popis: | PurposeTo evaluate visual function variations in eyes with age-related macular degeneration (AMD) compared to normal eyes under different light/contrast conditions using a time-dependent visual acuity testing instrument, the Central Vision Analyzer (CVA).MethodsOverall, 37 AMD eyes and 35 normal eyes were consecutively tested with the CVA after assessing best-corrected visual acuity (BCVA) using ETDRS charts. The CVA established visual thresholds for three mesopic environments (M1 (high contrast), M2 (medium contrast), and M3 (low contrast)) and three backlight-glare environments (G1 (high contrast, equivalent to ETDRS), G2 (medium contrast), and G3 (low contrast)) under timed conditions. Vision drop across environments was calculated, and repeatability of visual scores was determined.ResultsBCVA significantly reduced with decreasing contrast in all eyes. M1 scores for BCVA were greater than M2 and M3 (P |
| Databáze: | OpenAIRE |
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