Environmental and Dietary Exposures Near a Major Industrial Harbour (Fos-sur-Mer, France) Identified as a Significant Pathway for PCBs and PCDD/Fs Accumulation in Residents’ Blood Serum
Autor: | Khaled Douib, Maxime Jeanjean, Marie-Pierre Etienne, Annabelle Austruy, Julien Dron, Gautier Revenko, Philippe Marchand, Sylvaine Goix, Marine Periot, Philippe Chamaret |
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Přispěvatelé: | Institut Ecocitoyen pour la Connaissance des Pollutions [Fos-sur-Mer], Institut de Recherche Mathématique de Rennes (IRMAR), AGROCAMPUS OUEST, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Université de Rennes 2 (UR2), Université de Rennes (UNIV-RENNES)-École normale supérieure - Rennes (ENS Rennes)-Centre National de la Recherche Scientifique (CNRS)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA), AGROCAMPUS OUEST [Le Rheu], Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES), Laboratoire d'étude des Résidus et Contaminants dans les Aliments (LABERCA), Ecole Nationale Vétérinaire, Agroalimentaire et de l'alimentation Nantes-Atlantique (ONIRIS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Ecole Nationale Vétérinaire, Agroalimentaire et de l'alimentation Nantes-Atlantique (ONIRIS), Institut Ecocitoyen pour la Connaissance des Pollutions, Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-École normale supérieure - Rennes (ENS Rennes)-Université de Rennes 2 (UR2)-Centre National de la Recherche Scientifique (CNRS)-INSTITUT AGRO Agrocampus Ouest, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), École nationale vétérinaire, agroalimentaire et de l'alimentation Nantes-Atlantique (ONIRIS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), École nationale vétérinaire, agroalimentaire et de l'alimentation Nantes-Atlantique (ONIRIS) |
Rok vydání: | 2021 |
Předmět: |
010504 meteorology & atmospheric sciences
[SDE.MCG]Environmental Sciences/Global Changes Health Toxicology and Mutagenesis Context (language use) 010501 environmental sciences 01 natural sciences Blood serum Xanthoria parietina Environmental health Biomonitoring ComputingMilieux_MISCELLANEOUS 0105 earth and related environmental sciences Water Science and Technology computer.programming_language Pollutant biology [SDE.IE]Environmental Sciences/Environmental Engineering Public Health Environmental and Occupational Health biology.organism_classification Pollution Stratified sampling Geography 13. Climate action Harbour Control area [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie computer |
Zdroj: | Exposure and Health Exposure and Health, In press, ⟨10.1007/s12403-021-00395-8⟩ Exposure and Health, 2021, 13 (3), pp.447-464. ⟨10.1007/s12403-021-00395-8⟩ |
ISSN: | 2451-9685 2451-9766 |
Popis: | We investigated whether residents who lived closer to the core of one of the largest industrial zone in Europe (Fos-sur-Mer, France) had higher serum levels of organochlorine indicators (NDL-PCBs, DL-PCBs and PCDD/Fs) than people who lived out of the industrial core zone (Saint-Martin-de-Crau, France). The INDEX cross-sectional study was conducted from September to November 2016. We collected blood samples from 138 people (80 in the exposed area and 58 in the control area), which were included using a stratified random sampling method and selected with strict criteria (e.g., 30–65 years old, living in the area for at least 3 years, not working in the industrial sector, non-smoker). Biomonitoring indicators were calculated using multivariate linear regression models, adjusting for personal physiological, social, dietary, housing characteristics and free-time activities. We also measured these pollutants in samples of lichens (Xanthoria parietina) and atmospheric particles (PM2.5). We found that behaviours that involved environmental exposures (such as gardening, dietary history of consumption of vegetables, eggs, poultry, and local seafood) were significantly associated with an increase in organochlorine serum levels amongst residents of the industrial port zone compared to the residents of the control area. We also observed spatial and temporal variations of the pollutants across the territory. Our observations provided clues in understanding the presence of organochlorine compounds in the human body and links to environmental exposures in the context of one of the largest industrial zone in Europe. |
Databáze: | OpenAIRE |
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