Vitamin D deficiency as a predictor of severity in patients with COVID-19 infection
| Autor: | Fatma Mohammed Badr, Mohammed Abd El Monem Teama, Dina A. Abdelhakam, Marwa A Elmohamadi |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Multidisciplinary Coronavirus disease 2019 (COVID-19) business.industry Cross-sectional study SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) COVID-19 medicine.disease Vitamin D Deficiency Gastroenterology Severity of Illness Index vitamin D deficiency Immune modulator Cross-Sectional Studies Internal medicine Severity of illness Vitamin D and neurology Medicine Humans In patient business |
| Zdroj: | Science progress. 104(3) |
| ISSN: | 2047-7163 |
| Popis: | Background: As an immune modulator, vitamin D has been implicated in the coronavirus disease 2019 (COVID-19) severity. This study aimed to investigate the association between vitamin D levels and the severity of COVID-19 infection. Methods: A cross-sectional study, which included 124 patients diagnosed with COVID-19 and were selected from Ain Shams University Hospitals and assigned to two groups; mild and severe COVID-19. All patients underwent detailed history taking, clinical data, and different laboratory investigations as complete blood count, blood urea nitrogen, serum creatinine, liver enzymes, C-reactive protein, D-dimer, ferritin and serum vitamin D concentration. In addition to findings of initial chest computed tomography (CT) were recorded. COVID-19 Reporting and Data System (CO-RADS) and CT chest severity scores (CT SS) were reported. Results: In this study of 124 COVID-19-positive individuals, a high prevalence of hypovitaminosis D was found (97.6%). Lower vitamin D levels were significantly associated with more severe COVID-19 cases ( p-value Conclusion: The high frequency of hypovitaminosis D in severe COVID-19 patients provides further evidence of a potential link to poor prognosis and severity of the disease, so vitamin D deficiency may be a marker of poor prognosis in these patients. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|