Uranium gastrointestinal absorption: the F1 factor in humans
| Autor: | Renato Falcomer, Bliss L. Tracy, Jan M Zielinski, Dorothy P. Meyerhof, M. L. Zamora, Gerry Moodie |
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| Rok vydání: | 2003 |
| Předmět: |
Adult
Male Canada Water Pollutants Radioactive Metabolic Clearance Rate Administration Oral chemistry.chemical_element Radiation Dosage Intestinal absorption Absorption Gastrointestinal absorption Excretion Feces Sex Factors Animal science Sex factors Humans Ingestion Radiology Nuclear Medicine and imaging Radiometry Food Contamination Radioactive Aged Radiation Radiological and Ultrasound Technology Age Factors Public Health Environmental and Occupational Health General Medicine Middle Aged Uranium Calculation methods Intestinal Absorption chemistry Body Burden Environmental science Female Digestive System Duplicate diet |
| Zdroj: | Radiation Protection Dosimetry. 105:55-60 |
| ISSN: | 1742-3406 0144-8420 |
| Popis: | The present investigation was undertaken by the Department of Health, Canada, to determine the most appropriate value to use for uranium gastrointestinal absorption (f1) in setting the guideline for drinking water. Fifty participants, free from medical problems, were recruited from two communities: a rural area where drinking water, supplied from drilled wells, contained elevated levels of uranium and an urban area where the water supplied by the municipal water system contained < 1 microg l(-1). Uranium intake through food, drinking water and other beverages was monitored using the duplicate diet approach. Intake and excretion were measured by inductively coupled plasma-mass spectrometry (ICP-MS) in samples collected concurrently from the same individuals over a 3 d period. The range of f1 values was between 0.001 and 0.06, with a median of 0.009. These values were independent of gender, age, duration of exposure, daily total uranium intake and allocation of intake between food and water. Consistent with the recommendation of ICRP Publication 69, 78% were below 0.02. |
| Databáze: | OpenAIRE |
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