Supplementary Table S4 from MEN1309/OBT076, a First-In-Class Antibody–Drug Conjugate Targeting CD205 in Solid Tumors

Autor: Monica Binaschi, Andrea Pellacani, Stefano Manzini, Christian Rohlff, Keith E. Wilson, Jonathan Terrett, Carmel M. Lynch, Michael Trang, Dee Aud, Rahel Awdew, Phuoc Huy Pham, James E. Ackroyd, Rachel L. Dusek, San Lin Lou, Nickolas Attanasio, Sudha Swaminathan, Uyen T. Do, Robert Boyd, Angelo Kaplan, Arnima Bisht, Joaquin Arribas, Cristina Bernadó Morales, Rosanna Manno, Rossana Bugianesi, Massimiliano Salerno, Daniela Bellarosa, Corrado Carrisi, Alessandro Bressan, Mario Bigioni, Alessio Fiascarelli, Giuseppe Merlino
Rok vydání: 2023
DOI: 10.1158/1535-7163.22506912.v1
Popis: Supplementary Table S4: Antitumor activity of MEN1309/OBT076 on xenograft and PDX models with different CD205 antigen expression. a) PDX models.b) Score indicate the staining intensity. HE = heterogeneous. HO = homogeneous. c) TVI%, tumor volume inhibition, expressed as a percentage, indicates the ratio % between the mean of the tumor volume of the test article-treated group and the control treated with drug vehicle calculated at the Nadir of tumor growth.
Databáze: OpenAIRE