Diurnal variations of s-adenosyl-l-methionine and adenosine content in the rat pineal gland
| Autor: | B. Chabannes, N. Sarda, Henri Pacheco, L. Cronenberger |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
Male
S-Adenosylmethionine medicine.medical_specialty Adenosine Period (gene) Fractionation Biology Pineal Gland General Biochemistry Genetics and Molecular Biology Rat Pineal Gland S-Adenosyl-l-methionine stomatognathic system Internal medicine medicine Animals Circadian rhythm General Pharmacology Toxicology and Pharmaceutics Chromatography High Pressure Liquid Ultradian rhythm Rats Inbred Strains General Medicine Metabolism Circadian Rhythm Rats Endocrinology medicine.drug |
| Zdroj: | Life Sciences. 35:589-596 |
| ISSN: | 0024-3205 |
| DOI: | 10.1016/0024-3205(84)90253-4 |
| Popis: | S-adenosylmethionine and adenosine levels in the rat pineal gland were determined by high-performance liquid chromatography after fractionation of the pineal extracts. The concentration of S-adenosylmethionine follows a circadian rhythm and is about three times higher during the day (2.5 nmol/gland) than the night (1.1 nmol/gland). The variations in the level of adenosine are apparently more complex. Over the 24 hours period there are two maxima at 03.00 (120 pmol/gland) and 15.00 hrs (100 pmol/gland) and one minimum at 09.00 hrs (50 pmol/gland). In addition, only an ultradian rhythm with a period of 12 hrs and an acrophase of 3 hrs can be evinced by computer analysis. |
| Databáze: | OpenAIRE |
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