Serum Cytokine Responses in Primary Pneumonic Plague Patients
| Autor: | Ruifu Yang, Baiqing Wei, Xiaoyi Wang, Shouhong Yu, Zhaobiao Guo, Zuyun Wang, Hu Wang, Haoran Wang, Fuzhang Tian |
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| Rok vydání: | 2011 |
| Předmět: |
Microbiology (medical)
Pneumonic plague Time Factors medicine.medical_treatment Clinical Biochemistry Immunology Enzyme-Linked Immunosorbent Assay Bubonic plague Downregulation and upregulation medicine Humans Immunology and Allergy Interleukin 6 Plague biology Interleukin-6 medicine.disease Primary pneumonic plague Up-Regulation Serum cytokine Cytokine biology.protein Cytokines Tumor necrosis factor alpha Microbial Immunology |
| Zdroj: | Clinical and Vaccine Immunology |
| ISSN: | 1556-679X 1556-6811 |
| DOI: | 10.1128/cvi.00386-10 |
| Popis: | The serum levels of interleukin-2 (IL-2), gamma interferon (IFN-γ), tumor necrosis factor alpha (TNF-α), IL-4, IL-6, and IL-10 of pneumonic plague patients were determined by enzyme-linked immunosorbent assay. IL-6 was the only elevated cytokine in the patients, and its level increased with a clear time course, indicating that IL-6 might be a prognostic marker for predicting the progression of plague. |
| Databáze: | OpenAIRE |
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