Lone Aortic Insufficiency and Conduction Disease: A Marker of Reactive Arthritis

Autor:	Edward S. Katz, Mark Ettel, Geoffrey Lam, Robert Donnino, Abe DeAnda, Joshua M. Lader, Muhamed Saric
Rok vydání:	2014
Předmět:	Male medicine.medical_specialty Aortic Valve Insufficiency Physical examination Chest pain Arthritis Reactive Electrocardiography Aneurysm Internal medicine Humans Medicine Radiology Nuclear Medicine and imaging Reactive arthritis Sinus rhythm Atrioventricular Block HLA-B27 Antigen medicine.diagnostic_test business.industry Mechanical Aortic Valve Middle Aged medicine.disease Surgery First-degree atrioventricular block Aortic Valve Heart Valve Prosthesis cardiovascular system Cardiology medicine.symptom Cardiology and Cardiovascular Medicine business Biomarkers Echocardiography Transesophageal Uveitis
Zdroj:	Echocardiography. 31:E271-E274
ISSN:	0742-2822
DOI:	10.1111/echo.12691
Popis:	A 48-year-old male with history of chronic arthritis and uveitis presented with 1 year of progressively reduced exercise capacity and nonexertional chest pain. Physical examination was consistent with severe aortic insufficiency. An electrocardiogram demonstrated sinus rhythm with first degree atrioventricular block. Transthoracic and transesophageal echocardiography demonstrated severe lone central aortic insufficiency of a trileaflet valve due to leaflet thickening, retraction of leaflet margins and mild aortic root dilation in the setting of left ventricular dilatation. In addition, computed tomographic angiography revealed a small focal aneurysm of the distal transverse arch. He was found to be positive for the immunogenetic marker HLA-B27. The patient subsequently underwent uncomplicated mechanical aortic valve replacement. The diagnosis of HLA-B27 associated cardiac disease should be entertained in any individual with lone aortic insufficiency, especially if accompanied by conduction disease.
Databáze:	OpenAIRE
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