Effect of glycyrrhizin-containing toothpaste on dental plaque reduction and gingival health in humans. A pilot study
| Autor: | L. Brayer, I. Gedalia, S. Palmon, Lior Shapira, J. Goultschin |
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| Rok vydání: | 1991 |
| Předmět: |
Adult
Time Factors business.product_category Dental Plaque Gingival Hemorrhage Dentistry Pilot Projects Dental plaque Oral hygiene chemistry.chemical_compound Anti-Infective Agents Double-Blind Method Gingival health Humans Medicine Glycyrrhizin Toothpaste business.industry Dental Plaque Index Middle Aged Glycyrrhizic Acid medicine.disease Gingivitis chemistry Glycyrrhetinic Acid Periodontics Periodontal Index business Anionic detergent Toothpastes |
| Zdroj: | Journal of Clinical Periodontology. 18:210-212 |
| ISSN: | 1600-051X 0303-6979 |
| DOI: | 10.1111/j.1600-051x.1991.tb01136.x |
| Popis: | Glycyrrhizin, the main saponin of licorice, a surfactant producing aqueous gel, was tested for its effect on gingival health, as a supplemental agent in a toothpaste. 40 male and female volunteers brushed their teeth twice daily, with a toothpaste containing 0.25% and 0.50% glycyrrhizin, or a control toothpaste, respectively. All 3 toothpastes contained sodium lauryl sulfate as detergent. The subjects of the 3 groups were examined at days 0, 7, 14, 28, 35 and 42 for plaque, gingival and bleeding indices. The examiner was unaware of subject assignment. None of the brushing regimens with the experimental toothpastes induced significant changes in the examined indices, that were distinct from those observed with the control toothpaste. The decrease (insignificant) in the indices of the study period from 0 to 14 days may be considered as an increased oral hygiene awareness by the subjects examined. Possible explanations for the lack of efficiency in improvement of plaque, gingival and bleeding indices, may have been an insufficient glycyrrhizin concentration and/or chemical incompatibility in a toothpaste containing a mixture of an anionic detergent and an organic antibacterial surface agent. |
| Databáze: | OpenAIRE |
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