Heart failure assessed based on plasma B-type natriuretic peptide (BNP) levels negatively impacts activity of daily living in patients with hip fracture

Autor: Micihko Matsuura, Sumiko Shiba, Yusuke Tamamura, Toshio Nishikimi
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Male
Activities of daily living
medicine.medical_treatment
030204 cardiovascular system & hematology
Biochemistry
Severity of Illness Index
0302 clinical medicine
Interquartile range
Activities of Daily Living
Natriuretic Peptide
Brain
Natriuretic peptide
Medicine and Health Sciences
Biomechanics
030212 general & internal medicine
Musculoskeletal System
Aged
80 and over
Univariate analysis
Hip fracture
Multidisciplinary
Rehabilitation
Hand Strength
Age Factors
Regression analysis
C-Reactive Proteins
Treatment Outcome
Cardiology
Medicine
Female
Anatomy
Research Article
medicine.medical_specialty
medicine.drug_class
Science
Nutritional Status
Pelvis
03 medical and health sciences
Sex Factors
Internal medicine
Albumins
medicine
Humans
Skeleton
Aged
Retrospective Studies
Heart Failure
Hip
business.industry
Hip Fractures
Biology and Life Sciences
Proteins
medicine.disease
Health Care
Geriatrics
Heart failure
Quality of Life
Linear Models
business
human activities
Zdroj: PLoS ONE
PLoS ONE, Vol 15, Iss 8, p e0237387 (2020)
ISSN: 1932-6203
Popis: Several studies have shown that nutrition and muscle strength were associated with functional recovery in patients with hip fracture. However, the impact of heart failure on the improvement of activity of daily living (ADL) in patients with hip fracture have not been fully investigated. The purpose was investigating the effect of heart failure on the ADL improvement by rehabilitation in patients with hip fracture. A total of 116 patients with hip fracture discharged from our convalescent rehabilitation ward were studied. Heart failure was assessed based on plasma B-type natriuretic peptide (BNP) levels on admission. ADL was assessed based on rehabilitation effectiveness (REs), which was calculated using the FIM instrument. Clinical, demographic, and nutritional variables were measured. Multiple regression analysis was performed with REs as the dependent variable; variables showing significant correlation with REs in univariate analyses were selected as independent variables. Based on plasma BNP levels, we assigned 39 patients to a Low group: 22 (17-25) median (interquartile) pg/mL, 39 to a Middle group: 52 (42-65) pg/mL, and 38 to a High group: 138 (93-209) pg/mL. REs, handgrip strength, Hb, albumin, and GNRI were higher and age was younger in the Low group than High group (each p < 0.01, respectively). Multiple linear regression analysis revealed that age (p < 0.05), sex (p < 0.05), handgrip strength (p < 0.01), FOIS at admission (p < 0.01), rehabilitation time per day (p < 0.01), and BNP (p < 0.05) were significantly associated with REs. The effect of rehabilitation on ADL improvement was significantly blunted in the High group compared to the Low group. In conclusion, these results suggest that heart failure assessed based on plasma BNP levels negatively impacts improvements in ADL achieved through rehabilitation in patients with hip fracture.
Databáze: OpenAIRE
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