In vivo effect of UV-B on lymphocyte function
| Autor: | Kurt J. Bloch, John A. Parrish, Warwick L. Morison, Joel I. Krugler |
|---|---|
| Rok vydání: | 1979 |
| Předmět: |
Adult
medicine.medical_specialty Rosette Formation Time Factors Ultraviolet Rays Lymphocyte Stimulation Dermatology chemistry.chemical_compound Leukocyte Count In vivo Internal medicine Null cell medicine Humans Lymphocytes Phytohemagglutinins Phytohaemagglutinin biology Dose-Response Relationship Radiation Circadian Rhythm medicine.anatomical_structure Endocrinology chemistry Erythema Immunology biology.protein Thymidine Function (biology) DNA |
| Zdroj: | British Journal of Dermatology. 101:513-520 |
| ISSN: | 1365-2133 0007-0963 |
| DOI: | 10.1111/j.1365-2133.1979.tb15094.x |
| Popis: | SUMMARY Whole-body exposure of normal subjects to erythemogenic doses of UV-B radiation results in a decrease in the proportion of circulating E-rosette-forming lymphocytes, an increase in the proportion of null cells and a decreased incorporation of tridated thymidine into DNA of lymphocytes following stimulation by phytohaemagglutinin (PHA). These alterations are dose-dependent, appear soon after exposure, reach a maximum after 8–12 h, and are reversed by 48–72 h post exposure. |
| Databáze: | OpenAIRE |
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