The Evaluation of Small Intestinal Volvulus Caused by Pathogenic microorganisms in a Thoroughbred Mare
| Autor: | Hasti Daraei, Javad Javanbakht, Mohammad Noorisepehr, Meysam Jani |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
medicine.medical_specialty
Intestinal Compartments Small Intestinal business.industry Rectum Ileum Abdominal cavity medicine.disease Gastroenterology Surgery Volvulus Jejunum Cecum medicine.anatomical_structure Internal medicine Fecal Bacteria medicine Duodenum lcsh:Diseases of the digestive system. Gastroenterology Hemoperitoneum lcsh:RC799-869 medicine.symptom business |
| Zdroj: | International Journal of Enteric Pathogens, Vol 1, Iss 2, p 1 (2013) |
| ISSN: | 2322-5866 2345-3362 |
| DOI: | 10.17795/ijep13609 |
| Popis: | Background: Small intestinal (SI) volvulus is defined as a rotation of greater than 180 degrees about its mesentery of a segment of jejunum or ileum. Horses of all ages have been affected. There is typically an acute onset of signs of mild to severe pain. Objectives: The objective of this study was to evaluate the microbial pathogens of the duodenum, ileum, cecum, colon and rectum (feces) in associated with volvulus horse, and to determine whether rectal (fecal) samples are representative of proximal segments of the gastrointestinal tract. Materials and Methods: A brown 26 years old mare, BCS (body condition score) 4 was found dead in stall in the morning. It was moved to a suitable area to conduct a post-mortem exam. The mare was examined in hanging position and then left lateral-recumbent. Advanced abdominal tympany was present. Clinical signs, laboratory data, surgical or necropsy findings, clinic-histopathological findings and outcome for horse with SI volvulus was obtained from medical records, and identified by manual review. Horsefeces and colon were collected in autopsy. Fecal material was scooped from the center of a freshly defecated bolus into sterile sample cups, which were placed into plastic anaerobe jars with PackAnaero sachets (Mitsubishi Gas Co. via Remel, Lenexa, KS) and transported to the laboratory. Alternatively, colon contents were collected from horse at the autopsy by direct incision into the colon immediately after the horse was autopsied. The samples were transported anaerobically to the laboratory. Results: On opening the abdominal cavity; a large quantity of sanguineous, foul-smelling fluid with pus exited the perforated bowel wall (hemoperitoneum). Additionally, signs of an acute diffuse peritonitis were visible. The blood vessels of the stomach and intestines were distended. Small intestinal volvulus was observed in several segments (360 degree rotation involving the mesentery). This information may aid diagnosis and prognosis and guide to decision making for horses with this condition. Conclusions: The present study results can be used to make a scientific assessment of prognosis in the pre-operative, operative, and postoperative management of horses with small intestinal volvulus. Bacterial infectivity results from a disturbance in the balance between bacterial virulence and host resistance. The “objective” of bacteria is to multiply rather than to cause disease; it is in the best interest of the bacteria to kill the host. Rectal samples were not entirely representative of intestinal compartments in the small or large intestine. This should be taken into account when designing studies using fecal sampling to assess other intestinal compartments, suggesting that parts of the intestinal microbiota were unique to each animal in this study. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|