Nebulization of antimicrobial agents in mechanically ventilated adults in 2017: an international cross-sectional survey
| Autor: | Rosa Reina, Candela Solé-Lleonart, Stephan Ehrmann, Stijn Blot, Zhongheng Zhang, Emine Alp, Joana Alves, Maria Ruiz-Rodriguez, Jordi Rello, Matteo Bassetti, Andrew Conway-Morris, Despoina Koulenti, Enrique Teran |
|---|---|
| Přispěvatelé: | Conway Morris, Andrew [0000-0002-3211-3216], Apollo - University of Cambridge Repository, Service de Médecine Intensive Réanimation [Tours], Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), Centre d’Etude des Pathologies Respiratoires (CEPR), UMR 1100 (CEPR), Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM), UCL - SSS/IREC/MONT - Pôle Mont Godinne, UCL - (MGD) Services des soins intensifs |
| Rok vydání: | 2018 |
| Předmět: |
Microbiology (medical)
Infectious Diseases 0301 basic medicine medicine.medical_specialty medicine.drug_class Cross-sectional study 030106 microbiology Antibiotics [SDV.MHEP.PSR]Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract Anti-Infective Agents Cross-Sectional Studies Humans Respiration Artificial Respiratory Tract Infections Administration Inhalation Nebulizers and Vaporizers 03 medical and health sciences 0302 clinical medicine Internal medicine medicine In patient Medical prescription ComputingMilieux_MISCELLANEOUS business.industry Respiration General Medicine medicine.disease Antimicrobial 3. Good health Pneumonia Inhalation 030228 respiratory system Amikacin Artificial Administration Colistin business medicine.drug |
| Zdroj: | European Journal of Clinical Microbiology and Infectious Diseases European Journal of Clinical Microbiology and Infectious Diseases, Springer Verlag, 2018, 37 (4), pp.785-794. ⟨10.1007/s10096-017-3175-5⟩ Eur J of Clin Micr & Inf Dis : official publication of the European Society of Clinical Microbiology, Vol. 37, no. 4, p. 785-794 (2018) |
| ISSN: | 1435-4373 0934-9723 |
| DOI: | 10.1007/s10096-017-3175-5 |
| Popis: | 2017 ESCMID practice guidelines reported safety concerns and weak evidence of benefit supporting use of aerosolized antibiotics in mechanically ventilated patients. Our primary goal was to assess current patterns of aerosolized antibiotic prescription in mechanically ventilated patients. A sequential global survey was performed prior to the release of the ESCMID guidelines, from the 1st of February to the 30th of April 2017, using an electronic platform. Responses were analyzed comparing geographical regions. A total of 410 units responded, with 261 (177 from Europe) being eligible for the full survey. 26.8% of units reported not using aerosolized antibiotics. The two major indications amongst prescribing units were ventilator-associated pneumonia and ventilator-associated tracheobronchitis (74.3% and 49.4%, respectively). 63.6% of units indicated prescription solely in response to multi-drug resistant organisms. In comparison with a survey undertaken in 2014, there was a significant reduction in use of aerosolized antibiotics for prophylaxis (50.6% vs 7.7%, p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink