Association of obesity, diabetes, and physical frailty with dental and tongue-lip motor dysfunctions in patients with metabolic disease
| Autor: | Norio Nishioka, Kaoru Yamamoto, Toshihiko Shiraiwa, Taka-aki Matsuoka, Mitsuyoshi Takahara, Naoto Katakami, Iichiro Shimomura, Yoshifumi Maeno, Yoko Yoshida, Yuka Shiraiwa |
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| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Male medicine.medical_specialty Endocrinology Diabetes and Metabolism 030209 endocrinology & metabolism Gastroenterology 03 medical and health sciences 0302 clinical medicine Metabolic Diseases Tongue Diabetes mellitus Internal medicine Bayesian multivariate linear regression Linear regression medicine Diabetes Mellitus Humans Hyperuricemia Obesity 030109 nutrition & dietetics Nutrition and Dietetics Frailty Hand Strength business.industry medicine.disease Lip stomatognathic diseases medicine.anatomical_structure Female business Body mass index Dyslipidemia |
| Zdroj: | Obesity researchclinical practice. 15(3) |
| ISSN: | 1871-403X |
| Popis: | Objective This study aimed to reveal the clinical features associated with decreased dental (or shearing/crushing) and tongue–lip motor functions in patients with metabolic diseases. Methods One thousand patients with metabolic diseases including diabetes, dyslipidemia, hypertension, and hyperuricemia were recruited. Dental function was assessed with a gummy jelly test, wherein glucose elution from a chewed gummy jelly was measured. Tongue–lip motor function was measured as repeatedly pronounced syllables per second. The association of clinical variables with the two functions was analyzed using multivariate linear regression models. Results The mean measurement of dental function was 202 ± 73 mg/dL, and that of tongue–lip motor function was 5.5 ± 1.0 times/s. Clinical variables independently associated with dental function (mg/dL) were age (adjusted regression coefficient β = −9.8 per standard deviation [SD]), smoking (β = −14.4 and −25.9 for past and current smoking, respectively), body mass index (BMI) 25–30 and ≥30 versus 20–25 kg/m2 (β = −14.7 and −23.1, respectively), diabetes (β = −11.9), hemoglobin A1c level ≥64 mmol/mol (β = −14.6), gait speed (β = 6.2 per SD), and handgrip strength (β = 7.5 and 7.7 per SD for males and females, respectively) (all P Conclusions Obesity, diabetes, physical frailty, and old age were shared risk factors for decreased dental and tongue–lip motor functions in patients with metabolic diseases. |
| Databáze: | OpenAIRE |
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