The secretory patterns of relaxin and human chorionic gonadotropin in human pregnancy
| Autor: | Tadashi Uesato, Koichi Kato, Katsuyoshi Seki, Toru Tabei |
|---|---|
| Rok vydání: | 1985 |
| Předmět: |
endocrine system
medicine.medical_specialty Swine Pregnancy Trimester Third Radioimmunoassay Biology Chorionic Gonadotropin Human chorionic gonadotropin Endocrinology Pregnancy Internal medicine medicine Animals Humans Secretion reproductive and urinary physiology Relaxin urogenital system General Engineering medicine.disease body regions Pregnancy Trimester First medicine.anatomical_structure Pregnancy Trimester Second Hcg stimulation Female Corpus luteum hormones hormone substitutes and hormone antagonists Hormone |
| Zdroj: | Endocrinologia Japonica. 32:741-744 |
| ISSN: | 2185-6370 0013-7219 |
| Popis: | Relaxin and human chorionic gonadotropin (hCG) were simultaneously determined in the same serum samples obtained from pregnant women. Although the secretory pattern of relaxin, in general, appeared to parallel that of hCG during human pregnancy, several discrepancies were discerned in the secretory patterns of the two hormones. The mean hCG concentration significantly differed between weeks 4-7 and 8-11 of pregnancy, but the mean relaxin concentration did not. The mean relaxin concentration began to decrease at weeks 16-19 whereas that of hCG did so at weeks 12-15. The mean relaxin concentration at weeks 4-7 was significantly higher than that at weeks 24-27, though there was no significant difference between the mean hCG concentrations in the two periods. These differences in the secretory pattern of relaxin from that of hCG indicate that relaxin secretion in pregnancy is not determined only by the circulating level of hCG. The responsiveness of the corpus luteum of pregnancy to hCG stimulation of relaxin secretion may vary as a function of the age of the corpus luteum, and this may partially account for the differences between the secretory pattern of relaxin and that of hCG observed in the present study. |
| Databáze: | OpenAIRE |
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