Effectiveness of crystallization test in screening of potentially malignant oral disorders and oral cancer
| Autor: | Rashmi Naik, Ratna Kumari V N Tarigoppula, B R Ahmed Mujib |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Adult Male medicine.medical_specialty Histopathological grading oral potentially malignant disorder Gastroenterology Sensitivity and Specificity histopathological grading law.invention 03 medical and health sciences 0302 clinical medicine law Internal medicine Cupric chloride medicine Crystallization test Humans Mass Screening Crystallization General Dentistry Early Detection of Cancer Aged business.industry Diagnosis Oral General Medicine oral cancer Middle Aged oral squamous cell carcinoma lcsh:RK1-715 Solutions 030104 developmental biology 030220 oncology & carcinogenesis lcsh:Dentistry Carcinoma Squamous Cell Female Mouth Neoplasms business Copper |
| Zdroj: | Indian Journal of Dental Research, Vol 29, Iss 5, Pp 556-561 (2018) |
| ISSN: | 1998-3603 |
| Popis: | Aim: This study aims to determine the effectiveness of crystallization test in screening of oral potentially malignant disorders (PMDs) and oral cancer. Materials and Methods: Thirty patients of oral PMD, 30 patients of oral cancer and 40 normal healthy people were selected. One drop of blood was collected and added to 1 cc of double-distilled water at room temperature to get a final dilution of 6% hemolyzed blood. 0.1–0.2 cc of this blood sample is added to 10 cc of 20% cupric chloride solution and further is subjected to crystallization test. Results: In the normal healthy group, the pattern was typical with an eccentrically placed center of gravity with needles arranged in radiating fashion. Whereas in oral PMD and cancer groups, there was “transverse form” formation. This test had sensitivity and specificity of about 83.33% and 86.84% for PMDs group and 96.30% and 86.84% for oral cancer group respectively. Conclusion: Crystallization test was found to be sensitive, reliable, economical and less-invasive procedure for screening of oral PMDs and oral cancer. |
| Databáze: | OpenAIRE |
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