Effect of postural changes on cardiac and renal function in hypertensive subjects
| Autor: | Alberto C. Taquini, Pedro F. Aramendía, Villamil Mf, Fermoso Jd, I J de la Riva |
|---|---|
| Rok vydání: | 1962 |
| Předmět: |
medicine.medical_specialty
Cardiac output Renal ischemia urogenital system business.industry Posture Renal function Heart Kidney Cardiovascular physiology Excretion Endocrinology Renal physiology Internal medicine Renal blood flow Hypertension cardiovascular system medicine Humans medicine.symptom Cardiology and Cardiovascular Medicine business reproductive and urinary physiology Vasoconstriction circulatory and respiratory physiology |
| Zdroj: | American Heart Journal. 63:78-85 |
| ISSN: | 0002-8703 |
| DOI: | 10.1016/0002-8703(62)90223-5 |
| Popis: | The cardiac output (CO), renal blood flow (RBF), glomerular filtration rate (GFR), and excretion of electrolytes were studied in a group of 11 hypertensive subjects, who were placed first in a horizontal position and then in a semivertical position of 45 degrees. The average figures of the CO tended to be high. The RBF and the RBF/CO ratio were low, which was considered to be indicative of renal ischemia. The GFR was either normal or low, and the filtered fraction was high in all cases. The basal excretion of water and salt also tended to be high. The change to a semivertical position elicited a fall in the CO in 7 subjects, a rise in 2, and a lack of significant change in the other 2. The RBF fell in 9 subjects and remained unchanged in 2. There was no relationship between the variations in the CO and the RBF, so that the RBF/CO ratio showed variable changes. It rose slightly in 7 subjects and fell in 4; in 2 of these the fall was pronounced. This is interpreted as indicating that some hypertensive subjects with frankly diminished RBF are still able to respond with renal vasoconstriction to the stimulus of postural changes. The excretion of chloride, sodium, and water fell in a normal way during change of posture. |
| Databáze: | OpenAIRE |
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