Studies on an Interstitial Cell Tumor of the Testis:Formation of Cortisol-14C from Acetate-1-14C1
| Autor: | Robert E. Scully, Lewis L. Engel, Dorothy B. Villee, Gertrude Lanman |
|---|---|
| Rok vydání: | 1966 |
| Předmět: |
Male
medicine.medical_specialty Testicular tissue Hydrocortisone Endocrinology Diabetes and Metabolism medicine.medical_treatment Clinical Biochemistry Acetates In Vitro Techniques Biology Androsterone Biochemistry Steroid Endocrinology Testicular Neoplasms Internal medicine Hydroxyprogesterones medicine Humans Countercurrent Distribution Carbon Isotopes Biochemistry (medical) Interstitial cell tumor Lipids Hormones Cortisone Child Preschool Pregnenolone Autoradiography Steroids medicine.drug |
| Zdroj: | The Journal of Clinical Endocrinology & Metabolism. 26:381-392 |
| ISSN: | 1945-7197 0021-972X |
| DOI: | 10.1210/jcem-26-4-381 |
| Popis: | Slices of an interstitial cell tumor of the testis removed from a -yr-old boy were incubated with acetate-1-14C. Labeled androst-4-ene-3,17-dione, 11β-hydroxyandrost-4-ene-3,17-dione, androst-4-ene-3,11,17-trione, 3β-hydroxypregn-5-en-20-one, 17-hydroxypregn-4-ene-3,20-dione and cortisol were isolated. These results are discussed with reference to the steroid biosynthetic patterns observed in other human testicular tumors and in testicular tissue of other vertebrates. |
| Databáze: | OpenAIRE |
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