Long-term preservation of functional capacity and quality of life in advanced heart failure patients with bridge to transplant therapy: A report from Japanese nationwide multicenter registry

Autor: Takuma, Sato, Yuta, Kobayashi, Toshiyuki, Nagai, Takeshi, Nakatani, Jon, Kobashigawa, Yoshikatsu, Saiki, Minoru, Ono, Satoru, Wakasa, Toshihisa, Anzai
Rok vydání: 2022
Předmět:
Zdroj: International Journal of Cardiology. 356:66-72
ISSN: 0167-5273
Popis: Under the revised heart allocation system in the United States, bridge to transplant (BTT) patients with left ventricular assist device (LVAD) have a longer waitlist period, as they are now lowly prioritized. However, little is known regarding the long-term trajectory of functional capacity (FC) and health-related quality of life (HR-QOL) among BTT-LVAD patients.We retrospectively analyzed 442 consecutive patients with BTT-LVAD between April 2013 and May 2019 from a Japanese nationwide registry. FC (New York Heart Association [NYHA] functional class, peak oxygen uptake [VODuring the follow-up period of 30 months (IQR 18-42 months), 100 (22.6%) patients underwent transplantation, 37 (8.3%) died, and 14 (3.1%) underwent explantation for recovery. Mean peak VOBTT patients showed long-term preservation of FC and HR-QOL, suggesting that BTT remains an option despite the long waiting time to HTx.
Databáze: OpenAIRE
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