Cobalt-Catalyzed Regio- and Enantioselective Allylic Amination
| Autor: | Jia-Feng Chen, Samir Ghorai, Wen-Bin Xu, Sahadev Shrihari Chirke, Changkun Li |
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| Rok vydání: | 2019 |
| Předmět: |
Reaction conditions
chemistry.chemical_classification Allylic rearrangement Chemistry organic chemicals Enantioselective synthesis food and beverages chemistry.chemical_element General Chemistry 010402 general chemistry 01 natural sciences Biochemistry Catalysis 0104 chemical sciences Colloid and Surface Chemistry Organic chemistry Selectivity Cobalt Amination Alkyl |
| Zdroj: | Journal of the American Chemical Society. 141(29) |
| ISSN: | 1520-5126 |
| Popis: | The first earth-abundant cobalt-catalyzed highly branched- and enantioselective allylic amination of racemic branched allylic carbonates bearing alkyl groups with both aromatic and aliphatic amines has been developed. The process allows rapid access of allylic amines in high yields with exclusively branched selectivity and excellent enantioselectivities (normally 99% ee) under mild reaction conditions. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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