The use of biomedical sensors to monitor capsule formation around soft tissue implants
| Autor: | Jonathan W. Bender, Victor Giurgiutiu, M. L. Yost, C. Watson, Harold I. Friedman, M. Fitzmaurice |
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| Rok vydání: | 2005 |
| Předmět: |
Male
medicine.medical_specialty Piezoelectric sensor Strain (injury) Rats Sprague-Dawley chemistry.chemical_compound Silicone Materials Testing medicine Animals Strain gauge business.industry Foreign-Body Reaction Electric Conductivity Soft tissue Capsule Prostheses and Implants medicine.disease Surgery Electrodes Implanted Rats Amplitude chemistry Implant business Biomedical engineering |
| Zdroj: | Annals of plastic surgery. 56(1) |
| ISSN: | 0148-7043 |
| Popis: | Piezoelectric sensors have been shown to respond reproducibly to changes in tissue mechanical properties surrounding an implant over a 4-month period. The vibrational amplitude at a frequency corresponding to the radial resonance shows a statistically significant change over time. The initial period of inflammation is marked by a significant reduction in amplitude, which is indicative of an increase in viscous dissipation of the tissue. As collagen displaces the cellular response, the amplitude continues to decrease. Finally, as the tissue matures, the capsule becomes stiffer, and the viscous dissipation lessens. These results are consistent with qualitative assessments of explanted capsules. Strain gauges encased in a monolithic block of silicone exhibited a greater degree of variability, yet show similar trends over time. The strain increases in the initial 4-week period and remains relatively steady over the following 4 weeks. Beyond 8 weeks, the gauges begin to extrude from the animal or suffer a loss of electrical continuity. Steps are being taken to improve the strain sensor longevity in the animals. |
| Databáze: | OpenAIRE |
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