Which patients with advanced cancer and biliary obstruction benefit from biliary stenting most? An analysis of prognostic factors
| Autor: | Ahmet Taner Sümbül, Ali Ayberk Besen, Fatih Kose, Umut Dişel, Ozgur Ozyilkan, Sadık Muallaoğlu, Ahmet Sezer, Huseyin Abali, Levent Oguzkurt, Kamil Gurel, Ugur Ozkan |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
Male medicine.medical_specialty Colorectal cancer Biliary Stenting Malignancy Gastroenterology Internal medicine Pancreatic cancer Neoplasms Outcome Assessment Health Care medicine Confidence Intervals Humans Aged Retrospective Studies Aged 80 and over Medical Audit business.industry Cancer Middle Aged medicine.disease Prognosis Advanced cancer Survival Analysis Jaundice Obstructive Oncology Obstructive jaundice Female Stents Complication business |
| Zdroj: | Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer. 21(4) |
| ISSN: | 1433-7339 |
| Popis: | Patients with advanced cancer may present with obstructive jaundice. Biliary stenting is the treatment of choice. However, which patients benefit most is not well-defined, yet. Our aim was to delineate the clinical factors affecting prognosis. Charts of 140 patients with advanced cancer who underwent biliary stenting were retrospectively analyzed. Their median age was 63.5 years. Of these patients, 73 (52.1 %) were male, 32 (22.9 %) had ECOG PS 1 and 81 (57.9 %) had PS 2. The most frequent cancer types were cholangiocellular cancer (64, 45.7 %) and pancreatic cancer (36, 25.7 %). Median overall survival (OS) was 141 (95 % CI, 100.7-185.3) days. Female patients lived longer (161.0 vs. 124.0 days) (p = 0.036). Those patients with colorectal cancer lived the longest (667.0 days), followed by cholangiocellular (211.0 days), and gastric cancers (106.0 days) (p = 0.004). The distribution of primary diagnosis differed significantly between sexes: cholangiocellular cancer was present in 22 (30.1 %) out of 73 men and 42(62.7 %) out of 67 women (chi-square p |
| Databáze: | OpenAIRE |
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