Localization of coronary artery narrowings by applying R-wave amplitude correction to exercise-induced ST depression in angina pectoris and single-vessel coronary artery narrowing
| Autor: | Iwao Sotobata, Fumio Saito, Kazushige Kato, Mitsuhiro Yokota, Shoji Noda, Kiyoshi Hatano, Hiroshi Hayashi |
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| Rok vydání: | 1989 |
| Předmět: |
Male
medicine.medical_specialty Single vessel Coronary Angiography Angina Pectoris Angina Electrocardiography Internal medicine medicine Humans Circumflex Aged ST depression medicine.diagnostic_test business.industry Middle Aged medicine.disease Coronary Vessels Coronary arteries Stenosis medicine.anatomical_structure Cardiology Exercise Test Female medicine.symptom Cardiology and Cardiovascular Medicine business Artery |
| Zdroj: | The American journal of cardiology. 63(12) |
| ISSN: | 0002-9149 |
| Popis: | This study investigated whether coronary artery narrowings can be localized by applying R-wave amplitude correction to exercise-induced ST depression in multiple unipolar precordial lead electrocardiography using 20 electrodes covering the left chest wall. Ten normal subjects and 29 patients with stable angina pectoris and single-vessel coronary artery narrowing (greater than or equal to 75% luminal diameter stenosis in only 1-vessel) participated. Of the 29 patients, 5 had left main coronary artery disease (CAD), 14 had left anterior descending CAD, 4 had right CAD and 6 had left circumflex CAD. The exercise-induced ST depression with R-wave amplitude correction was defined as the exercise-induced ST depression divided by the R-wave amplitude. The 20 points of the lead system were divided into 4 areas: the left main, left anterior descending, right and left circumflex coronary arteries. Coronary artery narrowing was supposed to be in an artery corresponding to the area where the maximal value of the exercise-induced ST depression with and without R-wave amplitude correction was situated. By applying R-wave amplitude correction, the diagnostic ability of localization of coronary artery narrowings was improved significantly from 52% to 86% (p less than 0.005). In particular, localization of the left main coronary artery narrowing was correctly diagnosed in 100% (5 of 5) of angina pectoris patients with left main CAD. |
| Databáze: | OpenAIRE |
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