Onchocerciasis dynamics: modelling the effects of treatment, education and vector control
| Autor: | Nyimvua Shaban, Asha Hassan |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Insecticides
Disease status Computer science Population Basic Reproduction Number Disease Vectors trapping Models Biological 01 natural sciences ivermectin Ivermectin larviciding Statistics medicine Animals Population growth Computer Simulation 0101 mathematics education Health Education lcsh:QH301-705.5 Ecology Evolution Behavior and Systematics lcsh:Environmental sciences lcsh:GE1-350 education.field_of_study Vector control Ecology public health education 010102 general mathematics onchocerciasis Public health education Reproducibility of Results Numerical Analysis Computer-Assisted medicine.disease 010101 applied mathematics lcsh:Biology (General) Vector (epidemiology) Public Health Onchocerciasis medicine.drug |
| Zdroj: | Journal of Biological Dynamics, Vol 14, Iss 1, Pp 245-268 (2020) |
| ISSN: | 1751-3766 1751-3758 |
| Popis: | A deterministic model of onchocerciasis disease dynamics is considered in a community partitioned into compartments based on the disease status. Public health education is offered in the community during the implementation of mass treatment using ivermectin drugs. Also, larviciding and trapping strategies are implemented in the vector population with the aim of controlling population growth of black flies. We fit the model to the data to check the suitability of the model. Expressions are derived for the influence on the reproduction numbers of these strategies. Numerical results show that the dynamics of onchocerciasis and the growth of black flies are best controlled when the four strategies are implemented simultaneously. Also, the results suggest that for the elimination of the disease in the society there is a need for finding another drug which will be implemented to ineligible human as well as killing the adult worms instead of ivermectin. |
| Databáze: | OpenAIRE |
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