Rapid Respiratory Deterioration and Sudden Death Due to Disseminated Crypotcoccosis in a Patient With the Acquired Immunodeficiency Syndrome
Autor: | T A Rose, S Penmetsa, E D Crook |
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Rok vydání: | 1999 |
Předmět: |
Adult
Male Pediatrics medicine.medical_specialty Autopsy Pneumocystis pneumonia Sudden death Diagnosis Differential Death Sudden medicine Humans Glucocorticoids Mycosis AIDS-Related Opportunistic Infections Lung Diseases Fungal Respiratory distress business.industry Pneumonia Pneumocystis Respiratory disease Cryptococcosis Pneumonia General Medicine medicine.disease Immunology business |
Zdroj: | Southern Medical Journal. 92:927-929 |
ISSN: | 0038-4348 |
Popis: | We report the case of a patient with the acquired immunodeficiency syndrome (AIDS) whose death occurred within 30 hours of hospitalization due to disseminated cryptococcosis, manifested by dizziness, cough, and shortness of breath. The clinical picture was consistent with pneumocystis pneumonia, and antibiotic therapy with corticosteroids was initiated. Despite initial improvement, the patient's condition quickly worsened, resulting in cardiorespiratory arrest and death. Autopsy revealed cryptococci in several organs. Sudden, rapid deterioration and death are rare consequences of disseminated cryptococcosis, and steroids may worsen the course of the disease. On the basis of this case and review of similar cases in the literature, we recommend early consideration of disseminated cryptococcosis in AIDS patients with pneumonia. Early diagnosis and appropriate therapy are essential to reduce morbidity and mortality. |
Databáze: | OpenAIRE |
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