Rapid Respiratory Deterioration and Sudden Death Due to Disseminated Crypotcoccosis in a Patient With the Acquired Immunodeficiency Syndrome

Autor: T A Rose, S Penmetsa, E D Crook
Rok vydání: 1999
Předmět:
Zdroj: Southern Medical Journal. 92:927-929
ISSN: 0038-4348
Popis: We report the case of a patient with the acquired immunodeficiency syndrome (AIDS) whose death occurred within 30 hours of hospitalization due to disseminated cryptococcosis, manifested by dizziness, cough, and shortness of breath. The clinical picture was consistent with pneumocystis pneumonia, and antibiotic therapy with corticosteroids was initiated. Despite initial improvement, the patient's condition quickly worsened, resulting in cardiorespiratory arrest and death. Autopsy revealed cryptococci in several organs. Sudden, rapid deterioration and death are rare consequences of disseminated cryptococcosis, and steroids may worsen the course of the disease. On the basis of this case and review of similar cases in the literature, we recommend early consideration of disseminated cryptococcosis in AIDS patients with pneumonia. Early diagnosis and appropriate therapy are essential to reduce morbidity and mortality.
Databáze: OpenAIRE