Ischaemic stroke in young adults: predictors of outcome and recurrence
| Autor: | Luca Remonda, Urs Fischer, Heinrich Mattle, T A der Maur, Marcel Arnold, R W Baumgartner, Krassen Nedeltchev, Valeria Caso, Dimitrios Georgiadis, Matthias Sturzenegger, Gerhard Schroth |
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| Rok vydání: | 2005 |
| Předmět: |
Paper
Adult Male medicine.medical_specialty Adolescent Disease Transient ischaemic attacks Severity of Illness Index Brain Ischemia Predictive Value of Tests Recurrence Modified Rankin Scale Internal medicine Diabetes mellitus medicine Humans Prospective Studies cardiovascular diseases Age of Onset Young adult Stroke Neurologic Examination Vascular disease business.industry Middle Aged Prognosis medicine.disease Surgery Psychiatry and Mental health Etiology Female Neurology (clinical) business |
| Zdroj: | Journal of Neurology, Neurosurgery & Psychiatry. 76:191-195 |
| ISSN: | 0022-3050 |
| DOI: | 10.1136/jnnp.2004.040543 |
| Popis: | Background: There is limited information about predictors of outcome and recurrence of ischaemic stroke affecting young adults. Objective: To assess the predictive value of the presenting characteristics for both outcome and recurrence in young stroke victims. Methods: Clinical and radiological data for 203 patients aged 16 to 45 years were collected prospectively; they comprised 11% of 1809 consecutive patients with ischaemic stroke. The National Institutes of Health stroke scale (NIHSS), the Bamford criteria, and the trial of ORG 10172 in acute stroke treatment (TOAST) classification were used to define stroke severity, subtype, and aetiology. The clinical outcome of 198 patients (98%) was assessed using the modified Rankin scale (mRS) and categorised as favourable (score 0–1) or unfavourable (score 2–6). Results: Stroke was caused by atherosclerotic large artery disease in 4%, cardioembolism in 24%, small vessel disease in 9%, another determined aetiology in 30%, and undetermined aetiology in 33%. Clinical outcome at three months was favourable in 68%, unfavourable in 29%, and lethal in 3%. Thirteen non-fatal stroke, two fatal strokes, and six transient ischaemic attacks (TIA) occurred during a mean (SD) follow up of 26 (17) months. High NIHSS score, total anterior circulation stroke, and diabetes mellitus were independent predictors of unfavourable outcome or death (p |
| Databáze: | OpenAIRE |
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