Survival and predictors of mortality among patients admitted to the intensive care units in southern Ethiopia: A multi-center cohort study

Autor: Sofia Assen, Mengistu Yinges, Semagn Mekonnen Abate, Bivash Basu
Jazyk: angličtina
Rok vydání: 2021
Předmět:
medicine.medical_specialty
IRB
Institutional Review Board
Multivariate analysis
Referral
DURH
Dilla University referral hospital
law.invention
HURH
Hawassa university referral hospital
Hospital
IQR
Inter Quartile e Range
law
Intensive care
ICU
Intensive Care Unit
medicine
Intensive care unit
Mortality
Cohort Study
SOFA
Sequential Organ Failure Assessment
business.industry
CT
Computerized Tomography
Mortality rate
ARDS
Acute Respiratory Distress Syndrome
General Medicine
Odds ratio
SD
Standard Deviation
Institutional review board
SAPS
Simplified Acute Physiology Score
APACHE
Acute Physiologic and Chronic Health Evaluation
CI
Confidence Interval
AOR
Adjusted Odds Ratio
Emergency medicine
GCS
Glasgow Coma Scale
LOS
Length of Stay
STROBE
Strengthening the Reporting of Observational Studies in Epidemiology
Surgery
ACLS
advanced cardiac life support
BMI
Body Mass Index
business
WURH
Wolaita Sodo referral hospital
Cohort study
Predictor
Zdroj: Annals of Medicine and Surgery
ISSN: 2049-0801
Popis: Background The burden of life-threatening conditions requiring intensive care units has grown substantially in low-income countries related to an emerging pandemic, urbanization, and hospital expansion. The rate of ICU mortality varied from region to region in Ethiopia. However, the body of evidence on ICU mortality and its predictors is uncertain. This study was designed to investigate the pattern of disease and predictors of mortality in Southern Ethiopia. Methods After obtaining ethical clearance from the Institutional Review Board (IRB), a multi-center cohort study was conducted among three teaching referral hospital ICUs in Ethiopia from June 2018 to May 2020. Five hundred and seventeen Adult ICU patients were selected. Data were entered in Statistical Package for Social Sciences version 22 and STATA version 16 for analysis. Descriptive statistics were run to see the overall distribution of the variables. Chi-square test and odds ratio were determined to identify the association between independent and dependent variables. Multivariate analysis was conducted to control possible confounders and identify independent predictors of ICU mortality. Results The mean (±SD) of the patients admitted in ICU was 34.25(±5.25). The overall ICU mortality rate was 46.8%. The study identified different independent predictors of mortality. Patients with cardiac arrest were approximately 12 times more likely to die as compared to those who didn't, AOR = 11.9(95% CI:6.1 to 23.2). Conclusion The overall mortality rate in ICU was very high as compared to other studies in Ethiopia as well as globally which entails a rigorous activity from different stakeholders.
Highlights • The incidence rate of mortality among ICU patients was approximately fifty percent. • The main causes of ICU mortality were Trauma, Congestive heart failure, ARDS, and stroke respectively. • The cardiovascular and respiratory disorders were the commonest comorbidity among ICU patients. • All patients admitted to ICU experienced at least one complication during ICU stay.
Databáze: OpenAIRE
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