The neural basis of hostility-related dimensions in schizophrenia
| Autor: | Cinzia Perlini, Igor Nenadic, Paolo Brambilla, Bianca Besteher, Marcella Bellani |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Epidemiology
media_common.quotation_subject impulsivity Hippocampus Hostility Epidemiology for Behavioural Neurosciences Anger Impulsivity behavioral disciplines and activities Gyrus Cinguli urgency 03 medical and health sciences 0302 clinical medicine Neural Pathways mental disorders medicine Humans Prefrontal cortex Anterior cingulate cortex media_common Cerebral Cortex Brain Mapping neuroimaging hostility Public Health Environmental and Occupational Health Brain aggressiveness Amygdala medicine.disease 030227 psychiatry Aggression schizophrenia Psychiatry and Mental health medicine.anatomical_structure Schizophrenia Impulsive Behavior Schizophrenic Psychology medicine.symptom Psychology Insula 030217 neurology & neurosurgery Clinical psychology |
| Zdroj: | Epidemiol Psychiatr Sci |
| ISSN: | 2045-7979 2045-7960 |
| Popis: | Hostility and related dimensions like anger, urgency, impulsivity and aggressiveness have been described in non-clinical populations and various serious mental illnesses including schizophrenia. Although representing a mental healthcare challenge, the investigation of such constructs is often limited by the presence of complex and multi-factorial causes and lack of agreement in their conceptualisation and measurement. In this review, we aim to clarify the anatomical basis of hostility-related dimensions in schizophrenia. Imaging studies suggest malfunctioning of a neural circuitry including amygdala, striatum, prefrontal cortex, anterior cingulate cortex, insula and hippocampus to modulate hostile thoughts and behaviours, at least in the subgroup of patients with schizophrenia who exhibit high levels of urgency, impulsivity and aggressiveness. |
| Databáze: | OpenAIRE |
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