Antimicrobial stewardship program at a tertiary care academic medical hospital: Clinical, microbiological and economic impact. A 5-year temporary descriptive study
| Autor: | Fernando Barcenilla-Gaite, Alfredo Escartín Arias, María Fernanda Ramírez-Hidalgo, Dolors Castellana-Perelló, Montserrat Vallverdú Vidal, Santiago Manuel Cano Marrón, Miquel Falguera Sacrest, Alfredo Jover-Sáenz, Merce García González |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Multidrug-resistant organisms business.industry lcsh:Public aspects of medicine Incidence (epidemiology) Use antimicrobials Psychological intervention lcsh:RA1-1270 Antimicrobial stewardship Antibiotics cost Intensive care unit lcsh:Infectious and parasitic diseases law.invention Indirect costs law Emergency medicine Medicine lcsh:RC109-216 Original Research Article Economic impact analysis Descriptive research business Prospective cohort study |
| Zdroj: | Infection Prevention in Practice Infection Prevention in Practice, Vol 2, Iss 2, Pp-(2020) |
| ISSN: | 2590-0889 |
| DOI: | 10.1016/j.infpip.2020.100048 |
| Popis: | Introduction: Few prospective studies analyze, with sufficient duration, the impact of an antimicrobial stewardship program (AMSP) carried out entirely in a hospital. Methods: Descriptive study evaluating the consumption of antimicrobials expressed in defined daily doses (DDD) per 100 hospital occupied bed-days (OBDs) stratified in medical, surgical and intensive care unit (ICU) and the incidence of densities (ID) per 1,000 hospital OBDs of the prevalent multidrug-resistant organisms (MDRO) in a tertiary hospital, over a period of 5 years before and after the implementation of an AMSP. Analysis of direct costs and those associated with hospital stay and mortality. Results: A total of 32,802 patients with antibiotic treatment were included in the intervention period (2013–2017). Non-imposed advice was exercised in 14.9%. The degree of adherence to recommendation was 87.9%, direct treatment and de-escalation being the most frequently admitted interventions (P |
| Databáze: | OpenAIRE |
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