Comparison of growth factor levels in patients with normal and hypospadiac prepuce*
| Autor: | AHMET MURAT ÇAKMAK, MUSTAFA KEMAL ASLAN, PINAR ATASOY, EBRU ŞEBNEM AYVA, TUTKU SOYER |
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| Přispěvatelé: | Kırıkkale Üniversitesi |
| Jazyk: | turečtina |
| Rok vydání: | 2014 |
| Předmět: | |
| Zdroj: | Volume: 41, Issue: 1 81-85 Turkish Journal of Medical Sciences |
| ISSN: | 1300-0144 1303-6165 |
| Popis: | Joint Congress of British-Association-of-Pediatric-Surgeons/European-Pediatric-Surgery-Association -- JUN 17-20, 2009 -- Graz, AUSTRIA Soyer, Tutku/0000-0003-1505-6042 WOS: 000288413100011 Aim: To compare the growth factor levels in patients with normal and hypospadiac prepuce. Materials and methods: Patients who underwent hypospadias repair were included in the study. The prepuce was excised after achieving successful hypospadias repair with satisfactory functional and cosmetic appearance. The patients who underwent preputial reconstructions and complicated repairs were excluded. The control group consists of boys without hypospadias. Elective circumcision was performed to have normal preputial samples. The VEGF levels, VEGF receptor (VEGFR) and TGF-beta receptor (TGF-beta-R) expressions were evaluated in preputial tissues by immunohistochemical analysis. Results: Fifteen patients were included in each group. The mean age of patients with normal and hypospadiac prepuce was 4.33 +/- 1.39 and 4.07 +/- 1.58, respectively (P>0.05). Although VEGF, VEGFR, and TGF-beta-R levels were decreased in hypospadiac prepuce, statistical significance was detected only in VEGF levels (P |
| Databáze: | OpenAIRE |
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