Cyclic neutropenia. Clinical case report

Autor: Vicente Cuairán Ruidíaz, Violeta Magaña Barrios, Karla Ivette Oliva Olvera, Rodolfo Fragoso Ríos
Rok vydání: 2015
Předmět:
Zdroj: Revista Odontológica Mexicana. 19(4):e242-e248
ISSN: 1870-199X
DOI: 10.1016/j.rodmex.2015.10.015
Popis: Cyclic neutropenia occurs due to the fluctuation of cellular production levels of bone marrow stem cells. This is to say, they change during the cycle, and although numbers are recurrently low, function is normal. Cyclic neutropenia was first described by Leale in 1910 with dominant autosomal character. It manifests approximately every 21 days, with range of 14 to 36 days, lasting 3-6 days per episode. During the time when there are few circulating neutrophils, the patient is susceptible to infections. The clinical picture of this process includes: susceptibility to infection, feverish conditions, oral ulcers, impetigo, increased lymph nodes, periodontitis and stomatitis. It is important to stomatologically handle these patients; after inter-consultation with treating physician, prevent infection in a prophylactic scheme based on amoxicillin 50mg/per kg weight or clindamycin 20mg/per kg weight, review recent blood count results (maximum ten days before treatment). In emergency treatments pain and infection will be handled conservatively, with use of 0.12% chlorhexidine mouthwashes and Philadelphia solution when necessary.
Databáze: OpenAIRE