Association of right-to-left shunt with frontal white matter lesions in T2-weighted MR imaging of stroke patients
| Autor: | K. Alfke, Jian-Ren Liu, Axel Rohr, Robert Stingele, Björn-Moritz Plötz, Olav Jansen |
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| Rok vydání: | 2009 |
| Předmět: |
Adult
Male medicine.medical_specialty Right-to-left shunt Foramen Ovale Patent Comorbidity Nerve Fibers Myelinated Risk Assessment White matter Lesion Young Adult Paradoxical embolism Risk Factors Germany medicine.artery Internal medicine mental disorders medicine Humans Radiology Nuclear Medicine and imaging Stroke Aged Neuroradiology Aged 80 and over medicine.diagnostic_test business.industry Incidence Magnetic resonance imaging Middle Aged medicine.disease Magnetic Resonance Imaging Hyperintensity Surgery medicine.anatomical_structure Cardiology Female Neurology (clinical) medicine.symptom Cardiology and Cardiovascular Medicine business |
| Zdroj: | Neuroradiology. 51:299-304 |
| ISSN: | 1432-1920 0028-3940 |
| DOI: | 10.1007/s00234-009-0496-9 |
| Popis: | Cardiac right-to-left shunt (RLS), mainly due to patent foramen ovale (PFO), is a risk factor for paradoxical embolism and stroke. Results of studies about brain lesions in diffusion-weighted imaging (DWI) in PFO patients were controversial. DWI only detects acute ischemic lesions. We assessed the hypothesis that, in T2-weighted magnetic resonance imaging (T2WI) of stroke patients, RLS is associated with a typical distribution of small white matter lesions. In this retrospective case–control study, T2WI images of 162 stroke patients were evaluated. From stroke patients admitted between 1999 and 2003, 81 stroke patients with RLS were identified with contrast-enhanced transcranial Doppler (bubble test). Controls were 81 age-matched stroke patients without RLS (negative bubble test). In T2WI images, small lesions ( |
| Databáze: | OpenAIRE |
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