MUC5AC Levels Associated With Respiratory Syncytial Virus Disease Severity

Autor:	Fernando P. Polack, Evan L. O'Keefe, Courtney McCracken, Patricio L. Acosta, Curtis Travers, Mauricio T. Caballero, Devi Rajan, Sarah Geoghegan, Larry J. Anderson
Rok vydání:	2018
Předmět:	Male 0301 basic medicine Microbiology (medical) viruses Argentina Respiratory Syncytial Virus Infections macromolecular substances Mucin 5AC Nose Virus diseases Severity of Illness Index Virus 03 medical and health sciences Disease severity Severity of illness medicine Humans Respiratory system business.industry musculoskeletal neural and ocular physiology Mucin Infant Newborn Infant respiratory system 030104 developmental biology Infectious Diseases medicine.anatomical_structure ROC Curve nervous system Child Preschool Respiratory Syncytial Virus Human Immunology Biomarker (medicine) Female business Biomarkers
Zdroj:	Clinical Infectious Diseases. 67:1441-1444
ISSN:	1537-6591 1058-4838
DOI:	10.1093/cid/ciy340
Popis:	To assess MUC5AC as a biomarker for respiratory syncytial virus (RSV) disease severity, we tested nasal aspirates from RSV+ children with mild, moderate, and severe disease. Levels were significantly higher in those in the severe and moderate groups compared to mild group, indicating MUC5AC may be a useful biomarker for RSV disease severity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34fe606236119059ee779f8dbfebadc7 https://doi.org/10.1093/cid/ciy340 Zobrazit plný text záznamu