Dispensing of antibiotics, antitussives and mucolytics to asthma patients: a pharmacy-based observational survey
| Autor: | Liesl Osman, A El Hasnaoui, Geneviève Chamba, Gilles Devouassoux, Eric Van Ganse, Laurent Laforest, Gisele Bauguil |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male Pulmonary and Respiratory Medicine medicine.medical_specialty Adolescent Exacerbation Mucolytics Antitussives Pharmacy Anti-asthmatic Agent Treatment Refusal Antibiotics Internal medicine medicine Humans Anti-Asthmatic Agents Asthma Polypharmacy business.industry Odds ratio Middle Aged medicine.disease Anti-Bacterial Agents Surgery Antitussive Agents Drug class Multivariate Analysis Practice Guidelines as Topic Female Observational study Guideline Adherence business |
| DOI: | 10.1016/j.rmed.2007.08.004 |
| Popis: | Summary Background Antibiotics, antitussives and mucolytics are commonly used in asthma, despite limited evidence for their effectiveness. The correlates of use for these medication classes in asthma were identified. Methods Asthma patients aged 18–50 who were regular customers of pharmacies were included in an observational study. Patients completed a questionnaire, which was complemented by computerised pharmacy records of previously dispensed medications. Users of each drug class were compared to non-users in terms of demographics, asthma characteristics and management. Results Among 886 patients (mean age: 37; 55% females), 63.2%, 55.8% and 27.2%, respectively, were users of antibiotics, mucolytics and antitussives during the previous 12 months. In multivariate analysis, dispensing of >2 units of oral corticosteroids was the major correlate of receiving antibiotics (OR=5.47; 95% CI=[3.00–9.97]), mucolytics (OR=3.93; 95% CI=[2.38–6.50]) and antitussives (OR=1.86; 95% CI=[1.18–2.94]). Compared to well-controlled patients, the probability of receiving antibiotics was significantly higher for poorly controlled patients (OR=2.01; 95% CI=[1.28–3.15]). Conclusions Our results suggest that these drugs are mainly used during asthma exacerbations. A better understanding of the use of co-medication in asthma is required. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|